JASON D. JOSEPHSON

I'm pursuing my PhD in Chemistry at the University of Ottawa, presently developing new tools in bioorthogonal chemistry.
I'm interested in science, philosophy, religion, mathematics, art, and history.

Journal publications

Machine Learning Enabling the Prediction of Activation Energies of SPAAC.
Josephson, J. D.; Pezacki, J. P. & Nakajima, M. 2024, J. Phys. Org. Chem. In press.

Bioorthogonal reactions of oxadiazinones with strained trans-cyclooctenes.
Morrill, K.; Josephson, J. D.; Bilodeau, D. A.; Nakajima, M. & Pezacki, J. P. 2024, J. Phys. Org. Chem. In press.

3-Oxidopyridinium Ions Are Versatile Bioorthogonal Dipoles for Use in Cycloadditions with Cyclooctynes.
Serhan, M.; Josephson, J. D.; Masoud, S. S.; Nakajima, M. & Pezacki, J. P. 2024, Chem. Eur. J.

Optimized Bioorthogonal Non-canonical Amino Acid Tagging to Identify Serotype-Specific Biomarkers in Verotoxigenic Escherichia coli.
Strmiskova, M.; Josephson, J. D.; Toudic, C. & Pezacki, J. P. 2023, ACS Infect. Dis.

Photophysical Properties of Donor-Acceptor Stenhouse Adducts and Their Inclusion Complexes with Cyclodextrins and Cucurbit[7]uril.
Payne, L.; Josephson, J. D.; Murphy, R. S. & Wagner, B. D. 2020, Molecules.

Published artwork

Et al.
Josephson, J. D. 2022, Ottawa Design Club Zine 0004. Prose poetry.

Programs written

CubeContour
Github (2024)
Visualize Gaussian-generated .cube files.

MEpathGUI
Github (1.2.0, 2024) SourceForge (1.1.0, 2022)
PyQT-based GUI for creating energy level (PES/reaction coordinate) diagrams for physical chemistry.

Pedagogic materials

Introduction to Python for Chemistry Students (In progress...)

Digital artwork

Other artwork

Other projects

Formal education

Summa cum laude Honours BSc in Biochemistry with Minor in Asian Studies, University of Ottawa, 2021

Experienced in

Proficient with

Familiar with



Favicon made with Leon Rische's Generative Art with Context Free Grammars and accompanying code.
Last update: Dec 6, 2024